VIRUCIDAL EFFICACIES
The efficacy of Multi-Des GA is tested to ensure that it stays a powerful, high quality and up-to-date product. That’s why investments are made into putting Multi-Des GA to the test against emerging micro-organisms and pathogens.
Latest studies on Intra Multi-Des GA demonstrated its efficacy against veterinary viruses, by elimination of the worst-case virus. According to European standardized guidelines for biocides and disinfectants, Bovine Enterovirus is chosen as the worst case scenario virus in the veterinary field as it is one of the most resistant viruses to disinfection due to its non-enveloped, small and single-stranded RNA structure1. It is a virus within the same family of viruses that cause Foot-and-Mouth Disease, polio and parvoviral diarrhea.
In cooperation with an independent laboratory specialized at microbiological testing it was found the product was effective against Bovine Entero Virus, also known as the ECBO virus, when used at a concentration of 0.75%. The study was performed in accordance with the European Norm EN 14675. In addition, testing was performed under soiling conditions (presence of 3 g/l albumine) and at a temperature of only 10 °C to represent veterinary conditions (the lower the temperature, the lesser the disinfecting power). A 10log reduction of ≥ 4 was found meaning that more than 99.99% of the pathogen was eliminated , which passes the test criteria.
Figure 1: 3D structure of Bovine Enterovirus
Multi-Des GA has also been tested to be effective against Aujesky’s virus, which is a large, enveloped virus of the Herpes family. According to the resistance chart from Spaulding, 1957, as well as the subgrouping of viruses based on their resistance from Klein and Deforest2 ,viruses such as herpesviruses are more susceptible to disinfection in comparison due to their enveloped structure. Thus, it comes as no wonder that Multi-Des GA is also effective against Aujesky’s virus. Tests performed in Europe, according to the EN 14675 regulations, verify this. Klein-Deforest Virus subgrouping based on resistance Examples of viruses Effectivity of Multi-Des GA
Klein-Deforest Virus subgrouping based on resistance Examples of viruses Effectivity of Multi-Des GA

Klein-Deforest Virus subgrouping

based on resistance

Examples of viruses Effectivity of Multi-Des GA
A (enveloped viruses, least resistant) Influenza, herpes, retro

viruses

Yes

B (large, non-enveloped viruses,

mildly resistant)

Rota, adeno and

hepatitis B viruses

                     Yes

C (small, non-envoloped viruses,

highly resistant)

Entero, polio and

coxsackieviruses

Yes

1 Bieker, J.M., 2006, Chemical inactivation of viruses, Kansas State University, USA
2 Block, S.S., 2001, Disinfection, Sterilization and Preservation, Lippincott Williams and Wilkins, USA
Figure 2: As typically used today in healthcare facilities, with the decreasing level of resistance shown on the left, with examples of micro-organism types that are typical of each grouping and the equivalent levels of sterilization/disinfection. (Spaulding, 1957)