Veteglan

Product Description

d-Cloprostenol-based (sodium) prostaglandin analogue, to induce and synchronise oestrus in cows, to induce luteolysis in mares, to induce parturition in cows and sows, and to treat endometritis in cows, solution for injection.

Composition: Each ml contains: Active substance: d-Cloprostenol 0.075 mg as d-Cloprostenol sodium
salt 0.079 mg. Excipient: Citric acid, Chlorocresol 1.0 mg, Sodium hydroxide, Water for injections.
Clear and colourless aqueous solution.

Target species: Cattle (cows), pigs (sows) and horses (mares).

Indications for use: Cows: Synchronisation or induction of oestrus. Induction of parturition after day
270 of gestation. Treatment of ovarian dysfunction (persistent corpus luteum, luteal cyst). Treatment of
clinical endometritis with the presence of a functional corpus luteum and pyometra. Induction of abortion
up to day 150 of gestation. Expulsion of mummified foetuses. Delayed uterine involution. Therapy for the
treatment of ovarian cysts (9-14 days after initial administration of GnRH or analogue).
Sows: Induction of parturition after day 114 of gestation.
Mares: Induction of luetolysis in mares with a functional corpus luteum.

Contraindications: Do not use in pregnant animals unless it is desirable to induce parturition or
interruption of pregnancy. Do not use in animals with spastic dysfunctions of the gastrointestinal tract/or
respiratory system. Do not use in cows or sows who may have a dystocic parturition due to abnormal
position of a foetus, mechanical obstruction, etc.. Do not use in animals suffering cardiovascular or
respiratory diseases. Do not use by intravenous route. Do not use in case of hypersensitivity to the active
substance or to any of the excipients.

Dosage for each species, routes and method of administration: For intramuscular use.
Cows: 2 ml of the product / animal (equivalent to 150 µg d-Cloprostenol/animal)
Sows: 1 ml of the product / animal (equivalent to 75 µg d-Cloprostenol/animal)
Mares: 1 ml of the product / animal (equivalent to 75 µg d-Cloprostenol/animal)

Advice on correct administration: Cows:
Induction of oestrus (also in cows showing weak or silent heat): Administer the product after
determination of the presence of a functional corpus luteum (6th to 18th day of cycle). Heat usually
appears within 48-60 hours. Proceed to insemination 72 – 96 h after treatment. If there is no sign of
oestrus, the treatment may be repeated 11 days after the first injection.
Induction of parturition: administer the product after the 270th day of gestation. Parturition usually takes
place within 30 – 60 hours after treatment.
Synchronisation of oestrus: administer the product twice (within an interval of 11 days). Proceed with
inseminations 72 h and 96 h after the second injection.
Ovarian dysfunction: administer the product after determination of presence of corpus luteum. Then
proceed to inseminate at the first oestrus after injection. If oestrus does not take place, conduct a further
gynaecological examination, and repeat the injection 11 days after the first administration. Insemination
must always be carried out 72 – 96 hours after injection.
Clinical endometritis with the presence of a functional corpus luteum, pyometra: administer one dose
of the product. If necessary, repeat the treatment after 10 days.
Mummified foetus: Administer one dose of the product. Expulsion of the foetus is observed within 3-4
days after the administration of the product.
Induction of abortion: Administer one dose of the product in the first half of pregnancy.
Delayed uterine involution: administer one dose of the product and, if needed, carry out one or two
further treatments (within an interval of 24 hours).
Therapy for the treatment of ovarian cysts (9-14 days after initial administration of GnRH or
analogue): administer the product 9-14 days after verifying the positive response to treatment with GnRH
or analogue.
The rubber stopper of the vial can be safely punctured up to 10 times. Otherwise, for the 20 ml vials,
automatic syringe equipment, or a suitable draw-off needle, should be used to prevent excessive
puncture of the closure.

Withdrawal period: Cattle: meat and offal: zero days; milk: zero hours. Pigs: meat and offal: 1 day.
Horses: meat and offal: 2 days; milk: zero hours.

Marketing authorisation holder and manufacturer responsible for batch release: Laboratorios Calier, S.A., Spain